对于种族和少数民族参与者来说,临床研究互动尺度
Jennifer Y Kim1,2, Emily Botto1,2, Ruby Madison Ford1,2
1Tufts School of Medicine, Boston, Massachusetts.
JAMA network open
|May 13, 2025
概括
在临床试验中,低质量的患者与工作人员的互动减少了种族和少数民族患者的信任和重新注册的意愿. 新的临床研究相互作用量表可以帮助改善他们的临床试验经验和未来参与.
科学领域:
- 临床研究是临床研究.
- 卫生公平性健康公平性
- 患者的体验 患者的体验
背景情况:
- 种族和民族少数群体在临床试验中代表性不足.
- 患者与工作人员的互动显著影响入学决策.
- 需要一个验证的尺度来测量这些相互作用.
研究的目的:
- 开发和验证临床研究相互作用量表 (CRIS).
- 评估尺度能够衡量影响信任和重新注册意愿的相互作用的能力.
主要方法:
- 采访和在线调查的混合方法研究 (2023年4月至2024年6月).
- 规模验证涉及探索性和确认性因子分析.
- 结构方程建模评估了互动,信任和重新注册之间的规模有效性和关系.
主要成果:
- 22项CRIS显示出高可靠性 (α=0.96) 和有效性.
- 低质量的互动与信任度下降 (β=-0.56) 和重新注册的意愿 (β=0.80) 有关.
- 总样本大小为三个队列中的1113名参与者.
结论:
- 患者与工作人员的不良互动减少了少数群体患者的信任和未来参与.
- 克里斯是一个有价值的工具,用于改善少数群体患者的体验和临床试验的招生.
- 解决互动质量问题对于推动研究中的健康公平至关重要.
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