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Updated: May 15, 2025

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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TORC1通过Rag GTPase tether Tco8989自主控制其空间分区

Raffaele Nicastro1, Marie-Pierre Péli-Gulli1, Marco Caligaris1

  • 1Department of Biology, University of Fribourg, Fribourg, Switzerland.

Cell reports
|May 13, 2025
PubMed
概括

酵母利用Tco89将TORC1与Rag GTPases结合起来,调节Sch9激酶的活性. 通过酸化,TORC1稳定了Tco89,防止其降解,并维持TORC1的营养感应本地化.

关键词:
CP: 细胞生物学 细胞生物学科普:分子生物学 分子生物学拉格 GTPases 的使用方法在TORC1中,在Tco8989中使用.氨基酸信号传递方式增长控制 增长控制 增长控制拉帕米辛复合物的目标1 1

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