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Updated: May 15, 2025

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
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通过结合粘附分子A/miR-106b轴对糖尿病伤口愈合的转录后调节

Teng Gong1, Xiaoming Fan2, Minjuan Wu3

  • 1Burn & Wound Repair Department, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, Fujian 350001, China; Fujian Burn Institute, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, Fujian 350001, China; Fujian Burn Medical Center, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, Fujian 350001, China; Fujian Provincial Key Laboratory of Burn and Trauma, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, Fujian 350001, China.

Burns : journal of the International Society for Burn Injuries
|May 13, 2025
PubMed
概括

糖尿病伤口愈合受到JAM-A 3'-UTR的替代拼接的影响,导致过度的miR-106b释放. 这对状细胞的增殖和迁移产生调节障碍,阻碍了伤口的修复.

关键词:
糖尿病伤口 糖尿病伤口连接粘附分子A 连接粘附分子A这就是米RNA.缩短的剪接方式

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