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Updated: May 15, 2025

Visualization of Metabolites Identified in the Spatial Metabolome of Traditional Chinese Medicine Using DESI-MSI
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Visualization of Metabolites Identified in the Spatial Metabolome of Traditional Chinese Medicine Using DESI-MSI

Published on: December 16, 2022

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图像质谱在药物发现和开发中的现状:一项突出技术挑战和未来方向的调查

Yukari Tanaka1, Hiroyuki Yokoi2, Hidefumi Kaji3

  • 1Leader of Japan Association for Imaging Mass Spectrometry, Drug Metabolism and Pharmacokinetics and Analytical Sciences, Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, 3-1-1 Futaba, Toyonaka, Osaka, 561-0825, Japan.

Drug metabolism and pharmacokinetics
|May 13, 2025
PubMed
概括

图像质谱 (IMS) 面临着制药研究中的挑战. 最近的一项调查确定了样本准备和数据分析的关键问题,并提出了现实的标准化方法,以改善药物开发合规性.

关键词:
数据分析和可复制性药物的发现和开发.绘制图像的质谱仪.定量分析是一种量化分析.监管和合规问题 监管和合规问题样品的准备 样品的准备标准化和验证工作技术指南 技术指南组织分布 组织分布

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