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在小鼠接受CAR T细胞治疗后,与免疫疗法相关的认知障碍

Anna C Geraghty1, Lehi Acosta-Alvarez2, Maria C Rotiroti3

  • 1Department of Neurology and Neurosciences, Stanford School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.

Cell
|May 13, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞治疗可以通过引起持续的脑免疫反应来损害认知功能. 针对特定的免疫路径可以在CAR T细胞治疗后恢复认知能力和小质质健康.

关键词:
所有的治疗CAR T细胞美国美国国际贸易协会急性淋巴细胞白血病与癌症治疗相关的认知障碍化学物质扩散的中线质瘤免疫治疗相关的认知障碍微质细胞骨髓蛋白体细胞

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