用于exenatide口服的自乳化输送系统:疏水离子离子对与干逆

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Updated: May 17, 2025

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

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Marlene Ramona Schmidt1, Melanie Lena Ebert1, Magnus Andre Kiechle1

  • 1Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.

International journal of pharmaceutics
|May 13, 2025
PubMed
概括

两种新的策略,即疏水离子配对 (HIP) 和干逆 (dRM),显著提高了糖尿病药物埃克西纳提德的口服生物可用性. 这两种方法都显示出增强药物输送系统的前景.

关键词:
干燥的反向微粒.甲酸是一种甲酸.疏水离子离子配对口服的输送口服的输送这些是SEDDS.自体乳化药物输送系统自体乳化药物输送系统

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