乳腺癌患者报告的结果:为沉默和被遗忘的人辩护
Olivia Inez Solano1, Cora Withers1, Kirsten Allen2
1University of British Columbia, Department of Surgery, Kelowna, British Columbia, Canada; BC Cancer, Department of Surgical Oncology, Kelowna, British Columbia, Canada.
Clinical breast cancer
|May 13, 2025
概括
乳腺手术后患者报告的结果 (PROs) 显示,乳腺保护手术 (BCS) 提供了最高的满意度. 单独的乳腺切除术 (MA) 与重建乳腺切除术 (MR) 不逊色,但PRO参与需要改进.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 患者报告的结果
背景情况:
- 关于乳房保护手术 (BCS) 和乳房切除与重建 (MR) 的患者报告结果 (PROs) 的研究越来越多.
- 仅仅进行乳房切除术 (MA) 后的PROs存在有限的数据.
- 患者的程序选择是基于偏好,这强调了PROs对于知情决策的重要性.
研究的目的:
- 评估和比较患者报告的结果 (PROs) 在三个乳腺癌手术程序:BCS,MA和MR.
- 评估患者参与率在这些程序的PRO数据收集.
主要方法:
- 预期招募199名单边,非复发性乳腺癌患者 (2020年6月 - 2023年9月).
- 在手术前 (Q1),手术后 (Q2) 2-6周和手术后 (Q3) 1年进行BREAST-Q (BQ) 调查.
- 使用强迫多重回归分析来比较手术后的BQ分数.
主要成果:
- 实现了73.4% (146/199) 的参与率.
- 仅进行乳腺切除术 (MA) 的满意度与BCS相比较低,但相当于乳腺切除术与重建 (MR).
- 在所有手术中,身体健康状况都相似;在MR后,心理健康状况较低,但在MA后没有.
- 术前的BQ分数与所有领域的术后分数有很强的相关性.
结论:
- 乳腺节约手术 (BCS) 产生了最高的患者满意度和生活质量.
- 仅进行乳腺切除术 (MA) 与乳腺切除术与重建 (MR) 相比,显示出非劣质的结果.
- 改善患者参与PRO对于强大的研究结论,概括性和比较分析至关重要,特别是对于MA患者.
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