用于治疗勃起功能障碍患者的 Tribulus terrestris:随机试验的系统审查和元分析
Sally Suharyani1, Bella Amanda1, Jesselyn Angellee1,2
1Andrology Study Program, Department of Biomedical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, 60132, Indonesia.
International journal of impotence research
|May 13, 2025
概括
在勃起功能障碍 (ED) 的男性中,Tribulus terrestris显著改善了勃起功能得分. 这种药用草本比安慰剂有好处,副作用或水平没有显著差异.
科学领域:
- 草药是一种草药.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 综合医学是一个整体的医学.
背景情况:
- 勃起功能障碍 (ED) 是一种影响男性生殖健康的普遍疾病.
- 土地草是一种传统的药用草药,常常与增强性功能有关.
- 对Tribulus terrestris用于ED治疗的科学验证至关重要.
研究的目的:
- 系统地评估Tribulus terrestris在治疗ED方面的疗效和安全性.
- 用标准化结果措施分析其对勃起功能的影响.
- 为了在受控研究中比较Tribulus terrestris与安慰剂.
主要方法:
- 在主要数据库 (Cochrane,Medline,Scopus,欧洲PMC) 进行系统的文献审查.
- 包括随机对照试验评估Tribulus terrestris对ED的评估.
- 主要终点:国际勃起功能指数 (IIEF-5或IIEF-15).
- 使用随机效应模型对连续结果的元分析.
主要成果:
- 分析中包括了8项研究.
- 与基线相比,Tribulus terrestris显著改善了IIEF-5和IIEF-15分数.与基线相比,Tribulus terrestris显著改善了IIEF-5和IIEF-15分数.
- 在IIEF-5和IIEF-15分数方面,Tribulus terrestris表现出比安慰剂更高的疗效.
- 两组之间没有观察到总水平或不良事件发生率的显著差异.
结论:
- Tribulus terrestris 补充剂在提高ED患者的勃起功能方面似乎有效.
- 与安慰剂相比,这种草药具有良好的安全性,没有增加不良事件的风险.
- 进一步的研究可能会探索最佳剂量和长期影响,但目前的证据支持其用于ED.
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