在阻塞性左结肠癌中,术后解剖性泄漏的危险因素
Zhenzhen Liu1, Chaowei Zhang2, Binliang Zhao1
1Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou, 510630, People's Republic of China.
在阻塞性左结肠癌手术后,门泄漏 (AL) 风险与较高的BMI,较低的白蛋白 (ALB) 和大肠状况有关. 手术前的CT扫描可以帮助预测AL在接受切除和初级解剖 (RPA) 的患者.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 肠道泄漏 (AL) 是结肠癌手术后的一个关键并发症.
- 鉴定AL的风险因素对于改善患者在阻塞性左结肠癌 (OLCC) 一阶段切除和初级解剖 (RPA) 后的结果至关重要.
研究的目的:
- 调查OLCC的RPA后AL相关的因素.
- 为了确定独立的风险因素来预测这些患者的AL.
主要方法:
- 对人口统计,临床,手术内和病理学数据的回顾性分析.
- 包括手术前CT评估的脑海膜状况.
- 在AL和没有AL组之间进行比较;用于预测参数的接收器运行特征 (ROC) 曲线分析.
主要成果:
- 分析了141名患者 (15个AL,126个没有AL).
- 在身体质量指数 (BMI),白蛋白 (ALB),淋巴转移和门状况方面观察到群体之间的显著差异.
- 体重指数BMI,ALB和门状况被确定为AL的独立风险因素.
结论:
- 较高的BMI,较低的ALB,以及不封闭的阴囊 (通过CT进行手术前评估) 与AL风险增加有关.
- 这些因素可以帮助预测手术后的AL在接受RPA的OLCC患者中.
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