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Updated: May 2, 2026

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基于CRISPR的三模生物传感器用于miRNA检测:通过交叉验证改进临床诊断.

Jiangbo Dong1, Wenhao Ma1, Shiying Zhou1

  • 1Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, P. R. China.

Analytical chemistry
|May 13, 2025
PubMed
概括

我们开发了一种CRISPR/Cas12a驱动的三模生物传感器,用于超敏感的微RNA检测. 这种新的平台为潜在的早期癌症诊断提供可靠,快速和交叉验证的结果.

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相关概念视频

CRISPR and crRNAs02:53

CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
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