美国人口普查部门间肝细胞癌发病率趋势的差异,2001年至2021年
Itunu O Sokale1,2, Omar Rosales1, Aaron P Thrift1,2
1Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Cancers
|May 14, 2025
概括
肝细胞癌 (HCC) 发病率在全国范围内增加,但最近下降,具有显著的地理和种族差异. 有针对性的干预措施至关重要,以解决美国人口普查部门中HCC率的差异.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 肝细胞癌 (HCC) 是美国癌症死亡的主要原因.
- 了解HCC发病率的国家和地区趋势对于公共卫生倡议至关重要.
研究的目的:
- 提供对HCC发病率的国家世俗趋势的最新分析.
- 调查美国人口普查部门中HCC发病率的地理和种族/种族差异.
主要方法:
- 来自美国癌症统计数据库 (USCS) 的HCC发病率数据 (2001-2021年,不包括2020年) 的分析.
- 根据年龄调整的发病率使用国家癌症研究所的关节点回归计划进行了分析.
- 趋势是根据美国人口普查部门在全国范围内检查的,并按种族/种族分层.
主要成果:
- 国家HCC发病率从2001-2021年平均每年增加2.51%,但最近下降了-3.33% (2018-2021).
- 观察到区域差异很大,第1部门的下降幅度最大,第6和第7部门的下降率稳定.
- 最近的趋势表明,非西班牙裔黑人和亚洲/太平洋岛民人口大幅减少,其他群体的趋势不同.
结论:
- 全国HCC发病率正在下降,但这些趋势在所有美国人口普查部门或种族/种族群体中并不统一.
- 在不同人群中,HCC发病率仍然存在显著差异.
- 需要针对种族的公共卫生干预措施,以减少全国范围内的HCC发病率差异.
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