在西班牙裔老年患者中,代谢综合征和出血性中风患有脑洞形形
Alok K Dwivedi1, David Jang1, Ofek Belkin1
1Departments of Molecular and Translational Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
Diagnostics (Basel, Switzerland)
|May 14, 2025
概括
代谢综合征 (MetS) 与老年墨西哥西班牙裔患有脑洞性形 (CCM) 个体的出血性中风有关. 管理MetS和对于降低这些患者中风风险至关重要.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 大脑洞穴性形 (CCM) 会增加出血性中风的风险.
- 墨西哥西班牙裔人口的CCM和代谢综合征 (MetS) 患病率较高.
- 在西班牙裔CCM患者中,MetS和中风之间的联系尚不清楚.
研究的目的:
- 为了研究墨西哥西班牙裔CCM患者与对照者的心脏代谢概况.
- 在这个人群中评估MetS和出血性中风之间的关联.
主要方法:
- 墨西哥西班牙裔成年CCM患者和NHANES对照的回顾性队列分析.
- 使用费舍尔精确测试或未配对的学生t测试对风险因素进行比较.
- 对MetS和出血性中风相关的相对风险回归分析.
主要成果:
- CCM队列的和出血性中风率较高,但MetS患病率低于对照组.
- 在50岁及以上的CCM患者中,MetS与出血性中风相关 (RR = 2.38).
- 在墨西哥西班牙裔CCM患者中观察到明显的心脏代谢特征.
结论:
- 墨西哥西班牙裔CCM患者面临高出血性中风和的风险.
- 控制血压和管理MetS和对于预防中风至关重要.
- 对50岁以上的CCM患者来说,干预特别重要.
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