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Xu Deng¹, Taozong Guo¹, Yang He¹

¹Yunnan Provincial Key Laboratory of Animal Nutrition and Feed Science, Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.

Animals : an open access journal from MDPI

|May 14, 2025

概括

通过调节肠道微生物群,Parabacteroides goldsteinii (PG) 益生菌补充剂减少了小猪的肠道炎症. 这项研究证明了PG PG.

科学领域:

兽医医学兽医医学兽医医学
微生物学微生物学
免疫学免疫学免疫学

背景情况:

小猪的肠道炎症导致腹,免疫功能障碍和肠道功能障碍.
益生菌对于预防和管理小猪肠炎至关重要.
有限的研究存在于小猪中Parabacteroides goldsteinii (PG) 的抗炎作用.

研究的目的:

为了研究PG的抗炎作用和肠道微生物群调节在带有诱导肠道炎症的小猪身上.

主要方法:

德克斯硫酸 (DSS) 用于在50天大的DLY猪仔中在7天内诱导肠道炎症.
实验组在随后的7天内通过 gavage 接受了PG悬浮剂 (7.9 × 10^8 CFU/mL).
分析了血清细胞因子水平 (IL-6,IL-8,IL-10) 和肠道微生物组成.

主要成果:

DSS治疗显著改变了血清细胞因子水平,增加了IL-6和IL-8,同时减少了IL-10.
用PG给药使DSS治疗的小猪的细胞因子水平正常化.
补充PG丰富了有益的细菌,如乳杆菌和Butyricimonas,改变了α多样性,并影响了KEGG代谢途径.

结论:

黄石猪 (PG) 有效地缓解小猪的肠道炎症.
PG调节肠道微生物的组成,促进有益的细菌.
PG显示出作为益生菌的潜力,用于控制猪的肠道炎症和失生症.

关键词:

帕拉巴克特罗伊德斯金石种子肠道菌群是指肠道上的植物.肠道炎症肠道炎症小猪小猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪

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