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对加拿大商业杂交猪的腹部特征进行全基因组协会研究

Zohre Mozduri¹, Graham Plastow¹, Jack Dekkers²

¹Livestock Gentec Centre, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada.

Animals : an open access journal from MDPI

|May 14, 2025

概括

这项研究确定了影响猪腹部特征的关键遗传区域 (QTL),如脂肪含量和坚硬度. 这些发现为改善养猪计划和猪肉质量提供了新的标记.

科学领域:

动物遗传学动物遗传学
量化遗传学量化遗传学
分子生物学分子生物学

背景情况:

改善尸体特征对于养猪计划至关重要.
了解值,腹部坚硬度和脂肪沉积等特征的遗传基础对于猪肉质量至关重要.

研究的目的:

进行全基因组关联研究 (GWAS),以确定定量特征位点 (QTL) 和与关键猪尸体特征相关的基因.
发现用于提高猪肉质量和商业猪的脂肪成分的遗传标记.

主要方法:

来自1118只商业猪的全基因组测序数据 (杜洛克猪和约克郡/兰德雷斯F1母猪).
表型测量包括值,腹部坚硬度,腹部侧面脂肪,侧面总厚度,皮下脂肪和腹部.
使用低通序测 (SkimSeq) 和使用线性混合模型 (GCTA) 的GWAS分析进行基因型鉴定.

主要成果:

在SSC15上显著的QTL (110.83-112.23Mb) 与值相关,含有参与脂肪酸代谢的基因 (例如,COX15,SCD).
在SSC15上的PNKD,VIL1和PRKAG3基因与腹部度有关,影响肌肉结构和脂肪组成.
在SSC1,SSC2和SSC3上发现的腹部脂肪的三个QTL,涉及调节脂肪沉积的基因 (例如SLC22A18,PHLDA2).

结论:

已经确定了值,腹部坚硬度和腹部脂肪的新型分子标记物.
这些标记物可以整合到选择性育种计划中,以提高猪肉质量和脂肪分布.
这项研究促进了对控制体腹部特征的遗传机制的理解,有助于满足消费者偏好.

关键词:

QTLs 是一个 QTL.腹部的特征腹部的特征脂肪组成脂肪成分猪肉质量猪肉质量猪肉质量进行全基因组测序.

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