补充D-Glucuronolactone可以提高产卵的生产性能,蛋质量和肝脏健康
Yiru Shen1,2, Zhiqiang Miao1, Yuqi Zheng1
1Laboratory of Poultry Production, College of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Animals : an open access journal from MDPI
|May 14, 2025
概括
饮食中的D-glucuronolactone (DGL) 补充剂通过增强肝脏健康来改善产母母的表现. DGL增加了卵子的产量和质量,同时减少了肝损伤和炎症.
科学领域:
- 动物科学动物科学
- 营养生物化学 营养生物化学
- 禽畜科学 禽畜科学 禽畜科学
背景情况:
- 产母的肝脏对于新陈代谢和卵子生产至关重要.
- 高代谢需求可能导致肝脏的压力和性能降低.
- D-glucuronolactone (DGL) 是一种葡萄糖代谢物,具有已知的肝保护性质.
研究的目的:
- 调查食中的D-葡萄糖诺酸 (DGL) 对产量,蛋质量和产母的肝脏健康的影响.
- 确定DGL的最佳剂量,以改善母的性能和肝功能.
主要方法:
- 四百八十只Hy-Line棕母被食不同DGL水平的饮食 (0,70,140,280毫克/公斤).
- 评估的生产参数 (产卵率,蛋质量),蛋颜色,血清肝酶,肝指数和肝脂肪/三甘油含量.
- 评估肝脏组织病理学,抗氧化能力 (TAC,催化酶),炎症基因表达 (IL-1β,TNF-α,IFN-α,IL-6,IL-8) 和亡标志物 (FAS,Caspase 7,BAX).
主要成果:
- DGL补充剂显著增加了产卵率和蛋质量 (p < 0.05).
- DGL的使用加深了蛋的棕色,降低了血清肝酶 (AST,GGT) 和肝脂肪积累 (p <0.05).
- 肝保护作用包括改善肝膜,增强抗氧化活性,减少炎症和减少亡标志物.
结论:
- 饮食中的D-glucuronolactone (DGL) 通过改善肝脏健康,有效地提高产母的性能.
- DGL可以减轻肝脏的压力,炎症和亡,从而改善生产结果.
- 在这项研究中,用于改善性能和肝脏健康的最佳DGL剂量为280 mg/kg.
相关概念视频
Operons
Prokaryotes can control gene expression through operons—DNA sequences consisting of regulatory elements and clustered, functionally related protein-coding genes. Operons use a single promoter sequence to initiate transcription of a gene cluster (i.e., a group of structural genes) into a single mRNA molecule. The terminator sequence ends transcription. An operator sequence, located between the promoter and structural genes, prohibits the operon’s transcriptional activity if bound by a repressor...
Glucagon-like Receptor Agonists
Incretins include glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which stimulate insulin secretion post-meals. In type 2 diabetes, GIP's efficacy is reduced, making GLP-1 a viable drug target. GIP originates from preproGIP.
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by the...
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by the...


