塞拉提亚蛋白质与整合素的相互作用激活了促进入侵的信号通路

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Olga Tsaplina1

  • 1Institute of Cytology, Russian Academy of Sciences, Tikhoretsky av. 4, 194064 St. Petersburg, Russia.

International journal of molecular sciences
|May 14, 2025
PubMed
概括

塞拉蒂亚蛋白质使用其OmpX蛋白质与人类α5β1整合素受体结合,促进细菌入侵. 这种相互作用激活了涉及EGFR和FAK的信号通路,这对感染期间细胞骨变化至关重要.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.这是一种RGD.c-Src 激酶的作用焦粘附激酶 (FAK) 是一种聚焦粘附激酶.整合素结合激酶 (ILK) 是一种在 α5β1 整体中.

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