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细胞自主免疫:从细胞质感应到自卫

Danlin Han1, Bozheng Zhang1, Zhe Wang1

  • 1The First Clinical Medical College, Zhengzhou University, Zhengzhou 450052, China.

International journal of molecular sciences
|May 14, 2025
PubMed
概括

非免疫细胞通过细胞自主免疫,一种独特的防御机制对抗病原体. 本综述详细介绍了参与病原体检测和疾病致病的细胞质传感器和信号通路.

关键词:
细胞自主免疫的免疫力循环GMP-AMP合成酶 (cGAS) 刺激干扰素基因 (STING) 路径的刺激器.甘酸结合蛋白 (GBP) 是一种细胞内病原体 细胞内病原体视网膜酸诱导基因I (RIG-I) 类似受体 (RLRs) -线粒体抗病毒信号传导 (MAVS) 轴.

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