人体肠道微生物组:营养,新陈代谢和健康之间的连接器官
Sandra Valencia1,2, Martha Zuluaga3, María Cristina Florian Pérez2
1Centro de Bioinformática y Biología Computacional de Colombia-BIOS, Grupo de Investigación-BIOS, Parque los Yarumos, Manizales 170002, Colombia.
International journal of molecular sciences
|May 14, 2025
概括
个性化微生物组疗法,包括益生菌和益生菌,显示为管理慢性疾病的承诺. 医疗保健系统应该考虑这些肠道健康干预措施与传统治疗一起.
科学领域:
- 微生物学 微生物学
- 人类健康 人类健康 人类健康
- 代谢科学 代谢科学
背景情况:
- 肠道微生物群作为一种代谢器官,对营养吸收和整体健康至关重要.
- 饮食干预越来越被认为具有调节肠道微生物组的能力.
- 肥胖,糖尿病和炎症状况等慢性疾病与肠道功能失调有关.
研究的目的:
- 审查个性化微生物组向疗法的潜力,与慢性疾病的传统药物相比.
- 探索关键代谢途径和微生物代谢物的健康和疾病中的作用.
- 评估微生物组调制在临床实践中的整合.
主要方法:
- 使用Web of Science和Scopus数据库进行系统的文献审查.
- 对相关研究进行科学度分析.
- 探索像纤维发酵和短链脂肪酸生产这样的代谢途径.
主要成果:
- 饮食干预措施,包括增加纤维和益生菌摄入量,显示出在控制异位生物病方面的潜力.
- 微生物组调节会影响脂质和葡萄糖代谢,以及免疫系统的相互作用.
- 益生菌,益生菌和微生物群移植显示出对2型糖尿病和肥胖等疾病的治疗潜力.
结论:
- 微生物组调制策略需要纳入临床实践和研究.
- 综合营养,微生物学和生物化学的多学科方法是必不可少的.
- 个性化微生物组疗法可能为慢性疾病的传统药物治疗提供有价值的替代方案或补充.
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