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Updated: May 17, 2025

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向基因 C9orf72 肌缩侧面硬化症的发病因子

Zhao Zhong Chong1, Nizar Souayah2

  • 1Department of Neurology, New Jersey Medical School, Rutgers University, 185 S Orange, Newark, NJ 07103, USA.

International journal of molecular sciences
|May 14, 2025
PubMed
概括

基因C9orf72的六核酸重复扩张会通过有毒的功能增益和功能丧失机制引起肌缩性侧面硬化症 (ALS). 针对这些扩展对于开发有效的ALS疗法至关重要.

关键词:
在RNA重复中,RNA重复.骨髓缩侧面硬化症 (ALS) 是一种染色体9 开放的阅读框架 72滴重复的重复六核酸重复扩张的重复扩张

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