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Updated: May 17, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

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分子动力学模拟SPRED2Leu100Pro EVH-1域与神经纤维素的GAP相关域复杂

Martina Terrusa1, Elisa Sangiovanni1, Marialetizia Motta2

  • 1Department for Innovation in Biological, Agro-Food and Forest Systems-DIBAF, University of Tuscia, Via S. Camillo de Lellis s.n.c, 01100 Viterbo, Italy.

International journal of molecular sciences
|May 14, 2025
PubMed
概括

导致诺南综合征的SPRED2突变会影响蛋白质的稳定性和相互作用. 分子动力学模拟揭示了远程结构变化,而不是局部变化,导致功能丧失行为.

关键词:
诺南综合征是什么意思在 RAS 信号传输中.基本的动态 基本的动态分子动力学分子动力学神经纤维素瘤病 I 型含有芽相关的EVH-1域.

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