副作用对贫血治疗合规性的影响
Călina Ciont1,2, Raluca Maria Pop3, Ligia Pop1,2
1Department of Food Science, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
贫血治疗的副作用很常见,尤其是静脉注射铁. 老年和更高的BMI增加了严重程度,影响了坚持. 个性化管理对于更好的结果至关重要.
科学领域:
- 血液学 血液学 血液学
- 临床药理学 临床药理学
背景情况:
- 缺铁性贫血是一个全球性的健康问题.
- 治疗不良影响往往会阻碍患者的坚持和结果.
研究的目的:
- 调查罗马尼亚患者贫血治疗副作用的患病率和严重程度.
- 确定影响治疗坚持和患者满意度的因素.
主要方法:
- 未来的观察性横截面研究.
- 调查问卷分发给382名成人贫血患者.
- 收集有关人口统计,贫血原因,治疗方法和副作用的数据.
主要成果:
- 45%的患者报告了副作用;静脉注射铁的患病率比口服 (48%) 高 (52%).
- 常见的副作用:胃肠道 (恶心,胃烧) 和全身性 (疲劳,头痛).
- 增加的患者年龄和BMI与加剧的副作用严重程度相关,特别是胃肠道不适. 与治疗修改和较低的满意度相关的严重副作用. 和维生素D3显示出缓解副作用的潜力.
结论:
- 贫血治疗的副作用造成了很大的负担.
- 个性化管理策略对于改善坚持和临床结果至关重要.
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