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多发性硬化症的口腔表现:一个系统的审查
Paula García-Rios1, Francisco Javier Rodríguez-Lozano1, Miguel Ramón Pecci-Lloret1
1Gerodontologý and Special Care Dentistry Unit, Faculty of Medicine, Morales Meseguer Hospital, University of Murcia, IMIB-Arrixaca, 30008 Murcia, Spain.
Journal of clinical medicine
|May 14, 2025
概括
多发性硬化症 (MS) 与口腔健康问题,如口腔干燥和牙疾病有关. 早期识别和综合护理对于在MS患者中管理这些症状至关重要.
科学领域:
- 神经学 神经学
- 口腔医学是指口腔医学.
- 自免疫性疾病 自免疫性疾病
背景情况:
- 多发性硬化症 (MS) 是一种慢性中枢神经系统自身免疫性疾病,具有多种症状.
- 多发性硬化患者的口腔表现可能源于疾病本身或其治疗方法.
- 诸如异口症,牙周病和牙敏感性等症状会影响生活质量,并且经常被忽视.
研究的目的:
- 系统地审查多发性硬化症患者的口腔表现.
- 评估这些口腔症状的患病率和重要性.
- 探索口腔症状和MS临床参数 (表型,持续时间,残疾) 之间的相关性.
主要方法:
- 按照PRISMA指南进行系统审查.
- 数据库搜索 (PubMed,Scopus) 关于MS和口腔表现的观察性研究 (过去10年).
- 使用纽卡斯尔-太华尺度和JBI批判性评估检查清单进行质量评估.
主要成果:
- 纳入了10项研究,确定下,牙炎症,高DMFT/斑块指数,牙敏感性和口腔疼痛是常见的.
- 在口腔干燥和MS表型之间发现了显著的关联 (p < 0.05).
- 牙周健康与残疾水平有显著的联系 (p < 0.05).
结论:
- 多发性硬化和口腔健康问题之间存在明显的关联,特别是异口症和牙周病.
- 多学科护理对于MS患者的口腔健康管理至关重要.
- 需要使用标准化方案进行进一步的研究,以澄清MS的口腔系统相互作用.
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