如何评估精英耐力运动员的功能:不同基于肌素的配方的优缺点
Giuseppe Di Gioia1,2, Armando Ferrera1, Andrea Serdoz1
1Institute of Sports Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli, 1, 00197 Rome, Italy.
Journal of clinical medicine
|May 14, 2025
概括
与CG和MDRD方程不同,CKD-EPI和MCQE公式对于估计运动员功能是最可靠的. 这些发现有助于准确评估运动员的健康状况.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 运动医学 运动医学
- 生物标志物 生物标志物
背景情况:
- 以肌素为基础的方程用于估计膜过率 (eGFR) 在运动员中存在局限性.
- 准确的eGFR评估对于监测运动群体的功能至关重要.
研究的目的:
- 为了确定最合适的基于肌素的公式来估计奥运运动员的球过率 (eGFR).
- 为了比较四个eGFR方程 (Cockcroft-Gault,MDRD,MCQE,CKD-EPI) 在不同运动领域的性能.
主要方法:
- 评估了490名Olympic运动员的血清肌素正常,并且没有病史.
- 使用Cockcroft-Gault (CG),MDRD,MCQE和CKD-EPI公式计算了eGFR. 这是一个非常简单的方法.
- 将eGFR分类为KDIGO GFR类别 (G1-G5) 进行了分类.
主要成果:
- 与技能运动员相比,耐力运动员的血清肌素水平较高.
- CKD-EPI和MCQE公式在耐力和技能运动员之间显示出一致的eGFR结果.
- CG和MDRD公式在两组之间产生了显著的eGFR差异,CG低估了耐力运动员的eGFR,MDRD高估了耐力运动员的eGFR.
- CKD-EPI将所有运动员分类为G1,而CG和MDRD错误地将很大一部分运动员分类为G2.
结论:
- CKD-EPI和MCQE公式在运动员功能评估方面表现出卓越的稳定性和可靠性.
- 这些发现表明,CKD-EPI和MCQE是评估运动群体eGFR的首选方程.
- 准确的eGFR估计对于适当的健康管理和运动员表现监测至关重要.
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