对帕金森病中轻度认知障碍 (PD-MCI) 的基于计算机的认知训练的评估:A Review
Stamatia Kotsimpou1, Ioannis Liampas1, Metaxia Dastamani1
1Department of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41100 Larissa, Greece.
Journal of clinical medicine
|May 14, 2025
概括
计算机辅助认知干预 (CCT) 在轻度认知障碍 (PD-MCI) 的帕金森病中显著改善记忆和执行能力等认知功能. 然而,CCT对PD-MCI患者的心情的影响有限.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
- 数字健康数字健康
背景情况:
- 帕金森病中轻度认知障碍 (PD-MCI) 影响20-50%的患者,增加痴呆风险.
- 计算机辅助认知干预 (CCT) 正在探索提高PD-MCI的认知功能.
- 本审查评估了CCT的有效性和PD-MCI的最佳实施.
研究的目的:
- 评估基于计算机的PD-MCI干预措施的有效性.
- 为PD-MCI患者确定最有效的CCT方法.
主要方法:
- 随机临床试验 (RCT) 的系统审查.
- 在PubMed,谷歌学者和ScienceDirect搜索了2014-2024年发表的研究.
- 包括6个符合PD-MCI CCT干预资格标准的RCT.
主要成果:
- CCT在全球认知和执行功能方面表现出显著的改善.
- 在大多数研究中,没有观察到对情绪的显著影响.
- 六项研究符合审查标准,分析了PD-MCI中的CCT.
结论:
- 在PD-MCI中,CCT有效地增强认知功能,特别是记忆和执行能力.
- CCT对PD-MCI患者的情绪影响很小.
- 令人鼓舞的结果需要考虑未来研究中可能存在的方法偏差.
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