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Updated: May 15, 2025

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
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自免疫性胰腺炎:一篇评论

Varun Vemulapalli1, Cristina Natha1, Anusha Shirwaikar Thomas2

  • 1Department of Internal Medicine, UT Houston Health Science Center, Houston, TX 77030, USA.

Journal of clinical medicine
|May 14, 2025
PubMed
概括

自身免疫性胰腺炎 (AIP) 是一种罕见的胰腺炎症,有两种已知的亚型. 第三个亚型,免疫检查点抑制剂 (ICI) 诱导的胰腺炎,需要更新的诊断和治疗知识.

关键词:
在AIPIP中,AIPIP是AIP.在IgG4-RD的研究中,自己免疫性胰腺炎免疫检查点抑制剂免疫检查点抑制剂

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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The immune...
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