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治疗选择的趋势 对于早期的喉癌的治疗选择
Emily Y Huang1, Henry H Joo1, Sarek A Shen1
1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Journal of clinical medicine
|May 14, 2025
概括
跨口激光微手术 (TLM) 用于早期的喉癌 (EGC) 的使用正在慢慢增加,尽管外部光束放射治疗 (XRT) 仍然更常见. 治疗选择受到患者人口统计和保险状况的影响.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 跨口激光微手术 (TLM) 和外部光束放射治疗 (XRT) 对早期的喉癌 (EGC) 提供了类似的结果.
- 对EGC的治疗选择和患者人口统计的长度趋势需要研究.
研究的目的:
- 分析 EGC 用 TLM 与 XRT 的使用时间趋势.
- 确定与EGC治疗选择相关的人口因素.
主要方法:
- 从2004年至2017年期间从国家癌症数据库 (NCDB) 获取的T1-2N0M0喉癌病例的回顾性分析.
- 计算年度TLM与XRT比率 (TLM/XRT),按保险,教育,收入和设施位置分层.
- 应用单变量和多变量线性回归来评估TLM/XRT比率的趋势和人口影响.
主要成果:
- 在38428名EGC患者中,整体TLM/XRT比率从2004年的0.04增加到2017年的0.08.
- 在收入较高,私人/公共保险以及东北和西部地区观察到TLM/XRT的显著增加.
- 随着时间的推移,T1瘤,高等/低教育四分位数的TLM/XRT增加,但T2瘤或第二教育四分位数的TLM/XRT没有增加.
结论:
- 外部光束放射疗法仍然是EGC的主要治疗方法,但跨口激光微手术的使用正在逐渐增加.
- 患者保险状况,社会经济因素,地理位置和瘤T阶段与EGC越来越多地采用TLM相关.
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