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Updated: May 17, 2025

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在肥胖儿童中使用米达佐拉姆的生理基础和人口药动力学建模,使用现实世界的数据

Sean McCann1, Victória E Helfer1, Stephen J Balevic2

  • 1Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, Chapel Hill, North Carolina, USA.

Clinical and translational science
|May 14, 2025
PubMed
概括

这项研究检查了儿童的米达佐拉姆 (一种镇静剂) 剂量,发现肥胖稍微增加了药物暴露. 药物动力学建模表明,基于体重的剂量是关键,肥胖和非肥胖儿童之间的差异很小.

关键词:
米达佐拉姆 (Midazolam) 是一种药物.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖儿科 儿科 儿科 儿科药物动力学 药物动力学基于生理学的模型模型.人口模型的人口模型.

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