碳离子放射治疗在瘤学中的成本效益:系统性审查
Abdulrahman Bin Sumaida1, Nandan M Shanbhag2, Khalifa AlKaabi3,4
1Oncology/Radiation Oncology, Tawam Hospital, Al Ain, ARE.
Cureus
|May 14, 2025
概括
碳离子放射治疗 (CIRT) 对各种癌症具有成本效益,尽管初始成本较高. 这种先进的治疗提供了临床优势和有利的毒性概况,使其成为一个有价值的选择.
科学领域:
- 在瘤学瘤学.
- 放射疗法是一种放射治疗.
- 卫生经济学 卫生经济学
背景情况:
- 碳离子辐射疗法 (CIRT) 与光子和质子疗法相比,具有物理和生物上的好处,特别是在耐药瘤中.
- 由于高的基础设施和治疗成本,CIRT的广泛采用受到阻碍.
研究的目的:
- 与替代癌症治疗相比,系统地审查和评估CIRT的成本效益.
- 评估CIRT在不同癌症类型中的临床优势和毒性概况.
主要方法:
- 进行了系统的文献搜索,以确定相关研究.
- 包括5项涉及486名患有头骨底部胆瘤,直肠癌,肝细胞癌和非小细胞肺癌的患者的研究.
主要成果:
- CIRT表现出有利的成本效益比率,每生命年增加的增量成本高达88663美元.
- 对于复发性瘤,CIRT导致整体治疗成本降低.
- CIRT显示了有利的毒性概况,很少出现严重的不良事件.
结论:
- 尽管前期成本较高,但CIRT是各种癌症的经济有效和临床有益的治疗选择.
- 由于其优势,CIRT应在瘤实践中得到更广泛的考虑.
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