大脑刺激增强了PTSD的处置性正念:一个探索性的假控rTMS试验
Kaveh Rayani1, Andrea Grabovac1, Peter Chan1,2
1Department of Psychiatry, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Frontiers in psychiatry
|May 14, 2025
概括
重复的跨磁刺激 (rTMS) 可能会增强患有创伤后应激障碍 (PTSD) 的人的正念. 在三个月的随访中,观察到正念得分的好处,特别是非反应性,这表明效果延迟了.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
背景情况:
- 创伤后应激障碍 (PTSD) 是一种精神健康状况,其特点是过度警和回避等症状.
- 正念疗法和干预措施,如药物治疗和大脑刺激,在治疗PTSD方面表现出有效性.
- 针对背侧前额叶皮质 (DLPFC) 的非侵入性重复性经磁刺激 (rTMS) 已显示出调节情绪和减少PTSD症状的潜力.
研究的目的:
- 调查rTMS对被诊断患有PTSD的患者处置性正念的影响.
- 探索rTMS是否可以调节正念的特定组件,例如非反应性.
主要方法:
- 在试点,双盲,假控制试验的数据上进行了回顾性图表分析.
- 31名患有PTSD的参与者在两周内接受了积极的rTMS (1Hz或10Hz) 或假装治疗.
- 使用五方面正念问卷 (FFMQ) 在基线,治疗后和三个月的随访时评估正念.
主要成果:
- 接受rTMS的参与者最初显示了FFMQ总分的降低,在FDR调整后,这并没有保持显著.
- 在rTMS组中,从基线到三个月的随访期间,观察到总FFMQ得分和非反应性的显著改善.
- 这些发现表明,在rTMS治疗后,正念益处的出现可能会延迟.
结论:
- 初步数据表明,rTMS可能会增强患有PTSD的个体的处置性正念及其子组件.
- 进一步的研究是有必要的,以探索大脑刺激技术的实用性,以改善正念和PTSD的相关结果.
- 在更广泛的心理健康背景下,应用rTMS来增强心理健康值得进一步研究.
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