苏玛克水性提取物与饮食修改对功能性消化不良症状的影响与梅相比:一个开放标签,随机,受控的临床试验
Mahdi Saravani1, Zahra Memariani2,3, Nasser Behnampour4
1Golestan Research Center of Gastroenterology and Hepatology, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
苏玛克 (Rhus coriaria L.) 可能为功能性消化不良 (FD) 提供持久的补充治疗,比干预后的欧梅普拉更少的症状复发.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 药理学是指药理学,它是指药理学.
背景情况:
- 功能性消化不良 (FD) 是一种普遍存在的胃肠道疾病.
- 目前用于FD的治疗方法在长期有效性和症状复发方面存在局限性.
研究的目的:
- 研究Rhus coriaria L. (sumac) 作为功能性消化不良的补充治疗的治疗潜力.
- 为了比较 sumac 提取物,饮食变化和 omeprazole 对 FD 症状和生活质量的影响.
主要方法:
- 一项随机对照试验,涉及104名被诊断患有FD的患者 (ROME IV标准).
- 四个干预组:苏麦提取物+饮食变化,仅饮食变化,仅苏麦提取物和梅.
- 使用胃肠道症状评分表 (GSRS) 的症状评估和使用Nepean消化不良指数 (NDI-10) 的生活质量评估,持续八周.
主要成果:
- 在八周的干预期间,所有组的症状严重程度都下降了.
- 在第四周,没有观察到奥梅普拉和其他组之间症状严重性的显著差异.
- 干预后,症状严重程度增加,特别是在欧美普拉组,与其他组相比显示出显著的差异.
结论:
- 果提取物显示出作为功能性消化不良的有效补充疗法的潜力.
- 与梅相比,Sumac可能会提供更持久的治疗效果,症状复发率显著降低.
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