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Updated: May 16, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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通过氨酸扫描介绍 TRAIL 模仿和 DR5 之间的潜在绑定接口

Nitesh Mani Tripathi1, Arnab Chowdhury1, Neelam Verma1

  • 1Biomimetic Peptide Engineering Laboratory, Indian Institute of Technology, Ropar, Punjab 140001, India.

ACS medicinal chemistry letters
|May 14, 2025
PubMed
概括

研究人员绘制了激动剂和死亡受体5 (DR5) 之间的关键相互作用. 这种可以模仿 TRAIL,通过诱导亡,显示出开发新的癌症疗法的潜力.

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