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作为GSK3α抑制剂的新型异环胺衍生物

Yinlong Li1, Steven H Liang1

  • 1Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.

ACS medicinal chemistry letters
|May 14, 2025
PubMed
概括

新型皮里米丁衍生物选择性地抑制糖原合成酶激酶3α (GSK3α),显示出对结直肠癌治疗的希望. 这些化合物在临床前小鼠模型中显示出有效性.

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