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Updated: May 17, 2025

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通过GSK3活动调制,对GM-CSF依赖的膜巨细胞进行重新编程

Israel Ríos1, Cristina Herrero1, Mónica Torres-Torresano2

  • 1Myeloid Cell Laboratory, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.

eLife
|May 14, 2025
PubMed
概括

抑制GSK3通过调节MAFB,将巨细胞重新编程到一种抗炎,亲纤维状态. 这种巨细胞重编程是潜在的治疗目标,特别是在严重的COVID-19中.

关键词:
这是GSK3的GSK3.人类 人类 人类 人类 人类 人类 人类免疫学 免疫学 免疫学这是一种炎症炎症炎症炎症.大细胞重编程的重编程巨细胞是什么?巨细胞是什么?

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