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巴西新生儿的耳鼻裂:一个时间序列研究,2010-2021年

Karoline Machado Vieira¹, Verônica Canarim Menezes¹, Augusto César Cardoso-Dos-Santos²

¹Universidade do Sul de Santa Catarina, Curso de Medicina, Tubarão, SC, Brazil.

Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil

|May 14, 2025

概括

面腔裂,包括口腔裂和唇裂,在巴西各地分布多样. 南部地区患病率最高,而东北地区呈现出日益增长的趋势,不受COVID-19大流行影响.

科学领域:

流行病学流行病学
公共卫生公共卫生
遗传学是一个遗传学.

背景情况:

面腔裂是常见的先天性异常,具有重大公共卫生影响.
了解它们的地理分布和时间趋势对于有针对性的干预至关重要.

研究的目的:

从2010年到2021年,分析巴西2010年至2021年的口腔裂病例的分布和时间趋势.
将COVID-19大流行期间 (2020-2021) 的流行率与大流行前时期 (2010-2019) 的流行率进行比较.

主要方法:

一个流行病学时间序列研究利用活出生信息系统 (2010-2021).
流行率按年,地区和联邦单位计算.
普赖斯-温斯顿时间序列分析的通用线性模型.

主要成果:

全国口腔裂患病率为每1万活产婴儿中有6.73例.
南部地区为所有裂类型的患病率最高.
东北地区,阿拉戈阿斯和皮阿维显示出所有三种裂类型的上升趋势.

结论:

南部地区的口腔裂患病率最高,东北地区的患病率呈上升趋势.
阿拉戈阿斯和皮阿维州经历了所有三种裂类型的增加.
在分析期间,COVID-19大流行并没有显著影响巴西的面部裂患病率.

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