稀薄的空气,厚厚的血液:高海拔创伤中心增加了深静脉血栓症的发生率
Franklin L Wright1, Thomas J Schroeppel2, Michael R Bronsert1
1Department of Surgery, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
American journal of surgery
|May 14, 2025
概括
高海拔环境增加了创伤后深静脉血栓塞 (DVT) 的风险. 在4000英尺以上的设施中接受治疗的患者,与较低海拔地区的患者相比,DVT的发生率明显更高.
科学领域:
- 医学研究 医学研究
- 创伤外科手术是什么
- 静脉血栓塞栓症是一种静脉血栓塞栓症.
背景情况:
- 在海拔4000英尺以上接受手术的患者的深静脉血栓形成 (DVT) 率更高.
- 这种差异与在较低高度 (≤1000英尺) 接受治疗的患者相比较.
研究的目的:
- 调查创伤患者高海拔和深静脉血栓形成 (DVT) 率之间的关联.
- 在高海拔设施治疗的患者中量化DVT风险.
主要方法:
- 使用美国外科医生学院创伤质量改善计划 (TQIP) 数据库 (2014-2019).
- 在高海拔 (>4000英尺) 和低海拔 (<1001英尺) 接受治疗的成年人中,对比DVT的发生率.
- 采用多变量回归分析和倾向匹配模型进行比较.
主要成果:
- 高海拔地区DVT风险调整后几率比 (OR) 为1.53.
- 在受伤严重程度评分 (ISS) ≥16的患者中,高海拔与1.67的DVT OR相关.
- 倾向匹配模型表明,在更高的海拔上,DVT OR的值为1.59.
结论:
- 深静脉血栓形成 (DVT) 率在高海拔创伤治疗设施中较高.
- 高度是导致创伤后DVT风险增加的一个重要因素.
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