皮肤穿透冠状动脉干预结果根据5个主要种族和种族小组
Arjun B Kapoor1, Serdar Farhan2, Manish Vinayak2
1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
JACC. Advances
|May 14, 2025
概括
种族和民族差异影响皮肤冠状动脉干预 (PCI) 的结果. 南亚患者显示出更好的结果,而黑人患者面临更高的风险,表明需要有针对性的心血管保健策略.
科学领域:
- 心脏病学 心脏病学
- 医疗保健服务研究 医疗服务研究
- 健康差异 在健康上的差异
背景情况:
- 确定了心血管疾病 (CVD) 和穿皮冠状动脉干预 (PCI) 结果的种族和种族差异.
- 现有的研究往往无法区分像南亚和东亚人口这样的子组,这些人有不同的心血管疾病负担.
- 社会经济地位 (SES) 是PCI后不良结果的独立预测因素.
研究的目的:
- 分析白人,黑人,西班牙裔,南亚和东亚人群的1年PCI结果.
- 调查种族和种族对心血管结果的影响,考虑并发症和SES.
- 确定不同种族和民族群体在PCI结果中的特定差异.
主要方法:
- 从2012年到2022年接受PCI的21,236名患者的回顾性队列研究.
- 根据种族/种族和社会经济地位 (SES) 分层的患者,使用家庭收入中位数数据.
- 多变量考克斯回归模型评估了1年的主要心血管不良事件 (MACE),并调整了并发症和SES.
主要成果:
- 与白人患者相比,南亚患者的MACE显著降低 (调整HR:0.62;P<0.001).
- 与白人患者相比,黑人患者的MACE风险更高 (调整HR:1.27;P = 0.032).
- 在种族和民族之间观察到MACE的显著差异,即使在调整了并发症和SES之后.
结论:
- 在一年的PCI结果中仍然存在显著的种族和民族差异.
- 南亚患者表现出良好的结果,而与白人患者相比,黑人患者面临更糟糕的结果.
- 基线并发症和估计的SES并不能完全解释这些差异,因此需要针对不同人群进行有针对性的干预.
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