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Updated: May 5, 2026

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基素H2B异型H2bc27在小鼠胚胎发育中的大脑中得到表达

Saki Egashira1, Kazumitsu Maehara2,3, Kaori Tanaka2

  • 1Animal Life Science Laboratory, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 744 Motooka Nishi-ku Fukuoka, 819-0395, Japan.

Journal of biochemistry
|May 14, 2025
PubMed
概括

基因组H2B异型对基因调节至关重要. 这项研究确定了H2bc27在小鼠中的脑特异性,并揭示了它在调节大脑发育必不可少的基因中的作用.

关键词:
染色是一种染色素.发展/分化 发展/分化表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.基因表达 基因表达 基因表达希斯的异构形式

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The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...
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