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在关键尺寸缺陷中调节骨质免疫的生物织3D丝脚手架用于骨再生

Qian Zhang1, Zulan Liu1, YuanYuan He1

  • 1State Key Laboratory of Resource Insects, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715 China.

Journal of advanced research
|May 14, 2025
PubMed
概括

新的丝脚手架通过调节免疫反应和增强细胞生长来促进骨修复. 这种创新的生物材料为大骨缺陷提供了一个有前途的解决方案.

关键词:
3D生物连接脚手架架骨组织工程脚手架 骨组织工程脚手架平面丝虫子是一个平面丝虫子.免疫调节是一种免疫调节.骨质变异的分化 骨质变异的分化聚乳酸是一种多乳酸.

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...