发展的概念在管理的Desmoid瘤的管理
Sylvie Bonvalot1, Aisha Miah2, Bernd Kasper3
1Department of Surgical Oncology, Institut Curie, 26 rue d'Ulm, Paris 75005, France.
Hematology/oncology clinics of North America
|May 14, 2025
概括
状瘤 (DT) 的管理已经转向积极监测,为进展的病例保留治疗. 最近的试验为瘤提供了新的医学治疗见解.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 德斯莫体瘤 (DT) 是一种罕见的单克隆纤维细胞瘤.
- DT表现出不可预测的生物行为.
研究的目的:
- 审查瘤管理中的全球概念和策略的演变.
- 为了突出最近瘤治疗的进展.
主要方法:
- 在过去的15年中,对治疗方法的审查.
- 对最近随机临床试验的分析.
主要成果:
- 在大多数瘤病例中,从手术转向前线积极监测的显著转变.
- 大约50%的desmoid瘤表现为惰性疾病,而另一些需要治疗.
- 在desmoid瘤管理中,手术和放射治疗的适用性有限.
结论:
- 目前的desmoid瘤管理强调积极的监测.
- 新兴的医疗疗法对于精选的desmoid瘤患者至关重要.
- 全球对desmoid瘤的策略正在不断发展.
相关概念视频
The Tumor Microenvironment
6.5K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.5K
Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K


