在美国成年人中,动脉样硬化负担和肉症之间的关系:基于NHANES数据库的横截面研究
Scientific reports
|May 14, 2025
概括
血动脉质指数 (AIP) 与较低的肌肉质量和增加的肉类症风险有关. 这表明脂质新陈代谢对于肌肉健康和控制肉症至关重要.
科学领域:
- 老年学是指老年学的学科.
- 代谢健康 代谢健康
- 营养流行病学 营养流行病学
背景情况:
- 肉,肌肉质量和力量的下降,增加了脆弱性和死亡率.
- 血的动脉动原指数 (AIP),反映了脂质失衡,与萨尔科佩尼亚共享炎症和代谢途径.
- 了解脂质代谢和肉症之间的联系对于公共卫生至关重要.
研究的目的:
- 为了研究血 (AIP) 的动脉动原指数和肉类之间的关联.
- 为了确定是否脂质失衡,如AIP所示,是肌肉质量减少和肉症的危险因素.
主要方法:
- 从2011-2018年国家健康和营养检查调查 (NHANES) 的数据分析.
- 使用甘油三和高密度脂蛋白胆固醇计算AIP.
- 使用附骨肌肉质量指数 (ASMBMI) 对BMI进行调整,使用回归模型和脊柱曲线评估.
主要成果:
- 较高的AIP水平与ASMBMI的降低显著相关 (Beta = -0.02,P < 0.001).
- 较高的AIP与缩症风险增加有关 (OR = 2.6,P < 0.001),即使经过对混因素进行调整.
- 非线性关联和子组分析证实了AIP和肌肉健康指标之间的关系.
结论:
- 血动脉质指数 (AIP) 与肌肉质量减少和肉类症风险增加有显著联系.
- 根据AIP的指标,脂质代谢在维持肌肉健康方面发挥着至关重要的作用.
- 识别AIP作为可修改的风险因素为萨科佩尼亚管理提供了潜在的公共卫生策略.
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