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Updated: May 16, 2025

Merging Absolute and Relative Quantitative PCR Data to Quantify STAT3 Splice Variant Transcripts
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STAT5和STAT3平衡形状树突细胞功能和瘤免疫力

Jiajia Zhou1,2, Kole Tison1,2,3,4, Haibin Zhou5

  • 1Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.

Nature
|May 14, 2025
PubMed
概括

免疫检查点阻塞 (ICB) 的有效性依赖于树突细胞. 新研究显示,树突细胞中的STAT3和STAT5通路相互作用是ICB成功的关键,STAT3降解剂在癌症治疗中具有前景.

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