相关实验视频

Updated: Jun 16, 2025

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
11:24

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains

Published on: March 25, 2015

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通过IMiD独立的指域准转录因子

Bee Hui Liu1, Miao Liu2, Sridhar Radhakrishnan1

  • 1Cancer Science Institute of Singapore, Singapore, 117599, Singapore.

EMBO molecular medicine
|May 14, 2025
PubMed
概括

研究人员发现了SH6,一种降解SALL4蛋白的新型化合物,为针对SALL4表达癌症提供了一种新策略,这种策略与传统免疫调节性伊米德药物 (IMiD) 独立. 这一突破在临床前模型中显示出显著的瘤生长抑制.

关键词:
在C2H2中,它是C2H2.降解器降解器降解器这就是IMID的意思.在 SALL4 中,你会发现指集群四 (ZFC4) 是一个

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