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Updated: May 16, 2025

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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RING1决定了GSDMD介导的炎症反应和宿主对病原体感染的易感性

Yuanyuan Li1, Wenqing Gao1,2, Yuxin Qiu1

  • 1State Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Neurology, Huashan Hospital and School of Life Sciences, Fudan University, Shanghai, China.

Cell death and differentiation
|May 14, 2025
PubMed
概括

RING1通过Gasdermin D (GSDMD) 的无处不在,对宿主防御对细菌感染和败血症产生负面调节. 失去RING1会增加对病原体和炎症的易感性.

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