相关实验视频

Updated: May 17, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

3.0K

扩展性心肌病中的多基因风险评分:走向未来

Daria R Kramarenko1,2, Sean J Jurgens1,3,4, Yigal M Pinto1,2,5

  • 1Department of Experimental Cardiology, Amsterdam Cardiovascular Sciences, Heart Failure & Arrhythmias, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.

Current cardiology reports
|May 14, 2025
PubMed
概括

全基因组关联研究 (GWAS) 已经确定了与扩展性心肌病 (DCM) 相关的遗传变异. 从这些研究中获得的多基因分数 (PGS) 显示出评估DCM风险和指导患者管理的前景.

关键词:
心肌病是一种心肌病.在DCM中,DCM是指DCM.在GWAS中,GWAS就是GWAS.提供PGS服务.在PRS中使用PRS.

更多相关视频

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

10.9K
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

9.6K

相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.2K