在先天性玻璃眼瘤中,光盘形态
Arnav Panigrahi1, Nikhil Sawant1, Manzoor Ahmad Malik1
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Eye (London, England)
|May 14, 2025
概括
与健康儿童相比,患有初级先天性玻璃眼 (PCG) 的儿童表现出类似的光盘形态,包括尺寸,倾斜和扭曲. 然而,PCG眼睛表现出轴延长,这是先天性玻璃眼研究中的一个关键发现.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 先天性玻璃眼 (CG) 是一种严重的玻璃眼形式,在婴儿期出现.
- 光盘形态对于诊断和监测玻璃眼病至关重要.
- 了解CG中的光盘变化对于早期干预至关重要.
研究的目的:
- 为了比较光盘形态 (大小,倾斜,扭曲) 在患有先天性玻璃眼 (CG) 的儿童与健康的对照.
- 在CG中调查轴长,光盘面积,倾斜和扭转之间的关系.
- 为了区分初级先天性玻璃眼 (PCG) 和Axenfeld-Rieger形 (ARM) 之间的光盘特征.
主要方法:
- 涉及CG (PCG和ARM) 的儿童和年龄/性别匹配的健康对照的横截面研究.
- 底摄影和扫描激光眼镜镜被用于分析.
- 图像 J 软件量化了光盘倾斜和扭转;轴长和光盘面积被测量并相关联.
主要成果:
- 在PCG眼睛和健康对照之间,在光盘面积,倾斜或扭曲方面没有发现显著差异.
- 与对照人群相比,PCG眼睛的轴长显著更大,与光盘面积相关.
- 患有Axenfeld-Rieger形的眼睛显示磁盘扭曲明显高于对照组.
结论:
- 患有原发性先天性玻璃眼的儿童的光盘形态与健康个体没有显著差异,尽管轴延长.
- 轴延长是PCG眼睛的一个突出特征.
- 椎间盘扭曲可能是Axenfeld-Rieger形相关的玻璃眼的一个特征.
相关概念视频
Glaucoma: Overview
481
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
481
Anatomy of the Eyeball
5.8K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
5.8K
Angle Closure Glaucoma: Treatment
397
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
397
Photoreceptors and Visual Pathways
5.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.5K
Open Angle Glaucoma: Treatment
368
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
368


