心血管疾病和关节骨折之间的双向关联:系统性审查和元分析
Jinyi Wu1,2,3,4, Yan Zhang5, Junwen Wang3,4
1Fudan University School of Public Health, Xuhui, Shanghai, China.
BMC cardiovascular disorders
|May 14, 2025
概括
心血管疾病 (CVD) 和关节骨折 (HF) 显示出双向联系,中风和心力衰竭等疾病增加了HF风险. 关节骨折也会增加中风,心力衰竭和心血管疾病相关死亡的风险,这需要进一步的研究.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 心脏病学 心脏病学
背景情况:
- 调查心血管疾病 (CVD) 和关节骨折 (HF) 之间的复杂关系对于公共卫生至关重要.
- 了解这些疾病的双向性质可以为预防策略和患者护理提供信息.
研究的目的:
- 综合分析心血管疾病和关节骨折之间的双向关联.
- 综合现有关于心血管疾病和高频之间的联系的证据.
主要方法:
- 18个队列和病例控制研究的系统审查和元分析.
- 在多个数据库中进行了搜索 (PubMed,EMBASE,科学网等). ) 的情况.
- 使用纽卡斯尔-太华规模评估偏差风险;遵循PRISMA和MOOSE指南.
主要成果:
- 缺血性心脏病,中风,心力衰竭,高血压,脑血管疾病和动脉/动脉小板/毛细血管疾病与关节骨折风险增加有关.
- 骨折也与中风,心力衰竭,高血压,心肌梗塞和心血管死亡的风险增加有关.
- 亚组分析表明,缺血性心脏病和关节骨折之间的关联可能存在种族差异.
结论:
- 有证据表明,心血管疾病和关节骨折之间存在双向关联.
- 高异质性和潜在的混因素需要谨慎地解释研究结果.
- 需要进一步的机制研究来阐明心血管疾病和高频率之间的复杂相互作用.
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