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预后营养指数与双胞胎怀孕中产前有关

Qing Han^1,2, Shuisen Zheng², Xiaoling Chen¹

¹College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

BMC pregnancy and childbirth

|May 14, 2025

概括

预后营养指数 (PNI) 在双胞胎怀孕中较低. 较低的PNI表明双胞胎怀孕中发展PE的风险更高.

科学领域:

产科和妇科产科和妇科
孕产妇和胎儿医学孕产妇和胎儿医学
营养科学营养科学

背景情况:

孕前 (PE) 是双胞胎怀孕的一个重大并发症.
在双胞胎怀孕中早期评估PE的风险对孕产妇和胎儿的结果至关重要.
预后营养指数 (PNI) 反映了营养状况和免疫功能.

研究的目的:

调查第三个三个月的预后营养指数 (PNI) 与双胞胎怀孕中产前 (PE) 风险之间的关联.
确定PNI是否可以作为双胞胎妊娠中PE的预测标记.

主要方法:

一项队列研究包括2998例双胞胎怀孕,其中421例被诊断为PE.
随机森林算法 (Boruta包) 确定了PE的显著预测变量.
多变量后勤回归和ROC曲线分析评估了PNI和PE风险之间的相关性.

主要成果:

与对照组 (40.57 ± 3.63) 相比,PE组的PNI显著较低 (37.92 ± 3.86),而PE组的PNI显著较低.
较低的PNI独立地与双胞胎怀孕中PE风险增加有关 (OR = 0.780).
在预测PE时,ROC分析显示PNI的AUC为0.691,截止值为40.162.2.

结论:

预后营养指数 (PNI) 与双胞胎怀孕中产前风险有负相关.
在双胞胎怀孕中,PNI可能是评估风险和早期检测PE的宝贵工具.

关键词:

多变量逻辑回归的多变量回归孕前症孕前症预测营养指数的预测.随机森林算法随机森林算法双胞胎怀孕是什么意思双胞胎怀孕

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