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Updated: May 16, 2025

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
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虚拟查与相变FRET相结合,用于发现小分子FcRn对手

Gou Wu1, Yangjiayi Xiang2, Hongmei Liu1

  • 1Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University Pudong Medical Center & Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China.

Analytical chemistry
|May 14, 2025
PubMed
概括

研究人员开发了一种使用阶段过渡诱导的Förster共振能量转移 (PT-FRET) 的新选方法,以发现针对自身免疫性疾病的小分子新生儿Fc受体 (FcRn) 抗剂.

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