和吞性能的特定年龄的临床和大脑特征
Chia-Shu Lin1,2,3,4, Wei-Chieh Kao1
1Department of Dentistry, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Journal of oral rehabilitation
|May 15, 2025
概括
和吞的表现显示了年龄特定的与营养状况和大脑连接性的联系. 在老年人中,身体尺寸与表现相关,大脑连接性根据表现水平而异.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 生理学 生理学 生理学
背景情况:
- 和吞对于食物摄入至关重要,但个体表现的差异及其临床/神经学相关的研究不足.
- 了解这些过程对于维持整个生命周期的健康和功能至关重要.
研究的目的:
- 调查口腔,全身和营养因素与和吞性能之间的特定年龄关联.
- 用磁共振成像来探索这些表现和功能性大脑连接之间的关系.
主要方法:
- 118名健康的成年人 (年轻人,中年人,老年人) 接受了 (混合食物) 和吞 (唾液吞) 测试.
- 测量包括口腔,全身,营养因素 (例如,手臂/小腿周长) 和结构/静止状态fMRI.
- 基于种子的连接分析检查了传感器运动网络的功能连接 (rs-FC) 与吞性能相关.
主要成果:
- 吞性能与口腔/全身因素无关,与口不同.
- 在老年人中,更大的手臂/小腿周长与更好的和吞性能相关 (p=0.018).
- 拥有更高吞能力的老年人表现出更强大的小脑 - 基底 (rs-FC) (p=0.008);更高的能力与更强大的小脑 - 感觉运动皮层 (rs-FC) (p=0.045) 有关.
结论:
- 吞,口,营养状况和大脑功能连接之间存在特定年龄的关系.
- 这些发现强调了大脑在和吞能力的个体差异中的作用,特别是在老年人中.
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