利用乳酸菌:一种益生菌革命,用于对抗与代谢功能障碍相关的脂肪性肝病
Minwen Gu1, Qing Hong2, Jie Cui3,4
1College of Biological and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Critical reviews in food science and nutrition
|May 15, 2025
概括
乳杆菌益生菌通过改善肠道健康,有望减轻与代谢功能障碍相关的脂肪性肝病 (MASLD). 本综述探讨了这些有益细菌如何成为MASLD管理的非药物方法.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 微生物学 微生物学
- 代谢疾病 代谢疾病
背景情况:
- 代谢功能障碍相关的肥胖性肝病 (MASLD) 的特点是肝脏脂肪的积累,并与肠道失调有关.
- 乳酸菌是一种有益的益生菌,在低氧条件下壮成长,广泛应用于食品和卫生领域.
- 之前的研究表明,乳酸菌有可能改善MASLD,但详细的机制仍未总结.
研究的目的:
- 审查乳酸菌作为MASLD的非药物治疗策略的潜力.
- 总结一下临床前和临床证据,支持Lactobacillus在MASLD中的疗效.
- 阐明通过乳杆菌菌种改善MASLD的机制.
主要方法:
- 关于乳酸菌和MASLD的现有临床前和临床研究的全面审查.
- 分析了详细介绍各种乳酸菌种对MASLD的影响的研究.
- 检查在MASLD中对Lactobacillus的拟议作用机制.
主要成果:
- 乳杆菌菌株通过各种机制显示出减轻MASLD的潜力.
- 关键机制包括改善肠道屏障功能,减少炎症和减少氧化应激.
- 恢复有益的肠道代谢物是另一种重要的途径,通过该途径Lactobacillus发挥其作用.
结论:
- 乳酸菌代表了一种有前途的非药物治疗方法来管理MASLD.
- 对具体机制的进一步研究和更大的临床试验是必要的,以确认疗效.
- 乳酸菌和相关品种对未来的MASLD治疗策略具有潜力.
更多相关视频
10:31A Proboscis Extension Response Protocol for Investigating Behavioral Plasticity in Insects: Application to Basic, Biomedical, and Agricultural Research
Published on: September 8, 2014
34.3K
09:09Design and Construction of a Cost Effective Headstage for Simultaneous Neural Stimulation and Recording in the Water Maze
Published on: October 13, 2010
10.6K
相关概念视频
01:16Maximum Power Transfer
190
Numerous practical applications within engineering disciplines, such as telecommunications, necessitate optimizing power delivery to a connected load. This pursuit, however, entails inherent internal losses, which can either equal or exceed the power supplied to the load. The Thevenin equivalent circuit is helpful in finding the maximum power a linear circuit can deliver to a load. It is assumed in this context that the load resistance can be adjusted.
By substituting the entire circuit with...
By substituting the entire circuit with...
190
01:41Social Traps
22.2K
Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned...
22.2K
01:27Transformers in Distribution System
98
Transformers in distribution systems can be broadly categorized into distribution substation transformers and other distribution transformers. They are crucial for stepping down high transmission voltages to levels suitable for distribution and end-user applications.
Distribution substation transformers come in various ratings and typically use mineral oil for insulation and cooling. To prevent moisture and air from entering the oil, some transformers use an inert gas like nitrogen to fill the...
Distribution substation transformers come in various ratings and typically use mineral oil for insulation and cooling. To prevent moisture and air from entering the oil, some transformers use an inert gas like nitrogen to fill the...
98
01:24Bootstrapping
571
The term "bootstrap" originated in the 19th century as a metaphor for self-improvement or achieving something independently, without external assistance. This concept extends to statistical bootstrapping, a self-contained method for estimating population parameters through resampling, even though it can be computationally intensive. Developed by the American statistician Dr. Bradley Efron in 1979, bootstrapping provides a robust way to perform inference when the original sample size is...
571
01:25Control Systems: Applications
526
Electrical engineering plays a pivotal role in our daily lives, with control systems at the heart of many applications, from home appliances to sophisticated space shuttles. Control systems manage and regulate the behavior of devices and processes, ensuring they function safely, correctly, and efficiently.
In modern vehicles, control systems manage various functions to enhance performance and safety. The steering wheel and accelerator are primary inputs in a car's control system. The...
In modern vehicles, control systems manage various functions to enhance performance and safety. The steering wheel and accelerator are primary inputs in a car's control system. The...
526
01:22Imprinting
9.6K
Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
9.6K